Antinuclear antibodies

Abstract Antinuclear antibodies react with various nuclear autoantigens. Testing for them is critical for diagnosing connective tissue diseases, but they may be also found in other inflammatory diseases and in the elderly. They constitute a group of heterogeneous autoantibodies, and their specificity helps to discriminate between various connective tissue diseases. Screening for total antinuclear antibodies […]

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DefinitionAntibodies are proteins produced in vertebrates in response to certain substances. Antibodies are an important part of humoral immunity (which is mediated by antibodies). They are part of the gammaglobulin fraction and are also called immunoglobulins (Ig). Antibodies are produced by the body when B cells come into contact with a corresponding antigen. The B […]

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Improving health

How are NIBIB-funded researchers using computational modeling to improve health? Modeling infectious disease spread to identify effective interventions. Modeling infectious diseases accurately relies on numerous large sets of data. For example, evaluation of the efficacy of social distancing on the spread of flu-like illness must include information on friendships and interactions of individuals, as well […]

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